Ayurvedic Avipriya.
516 Premna integrifolia Linn.
Action Root and leaves—given in asthma, rheumatism.
The root contains several diterpenoids. Quinonemethide (bharangin) is reported from the plant.
Premna integrifolia Linn.
Synonym P obtusfolia R. Br.
P corymbosa auct. non Rottl. & Willd.
Family Verbenaceae.
Habitat Indian and Andaman
Coasts, plains of Assam and Khasi hills.
English Headache tree.
Ayurvedic Agnimantha (Kerala), Shriparni, Jayee, Ganikaarikaa,
Vaataghni.
Siddha/Tamil Munnai
Folk Agethaa, Ganiyaari.
Action Carminative, galactagogue. The tender plant is used for neuralgia and rheumatism. A decoction of
leaves is used for flatulence and colic.
Aqueous extracts of the plant showed a powerful action on the uterus and gout of the experimental animals, causing a marked increase in their activity.
The leaves contain an isoxazole alkaloid premnazole, which was found to reduce granuloma formation in rats (34.62%), its activity was comparable to phenylbutazone (35—36%).
Premnazole also reduced GPT and GOT in serum and liver. Studies suggest that premnazole acts probably by
controlling the activity of the adrenocorticotropic hormone.
Dosage Leaf, root bark—50— 100 ml decoction, powder—1—3 g.
(CCRAS.)
Premna latifolia Roxb.
Family Verbenaceae.
Habitat Peninsular India, Bihar, West Bengal and North-eastern India.
