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lactones of which parthenolide, a ger macanolide is the major component. It has been shown that Feverfew extract inhibits prostaglandin production and arachidonic acid release (this activity, at least partly, explains the herb’s antiplatelet and antifebrile action). The extracts also inhibit secretion of serotonin from platelet granules and proteins from polymorphonuclear leucocytes (PMN’s). Since serotonin is implicated in the aetiology of migraine and PMN secretion is increased in rheumatoid arthritis. Feverfew is used in migraine and rheumatoid arthritis. (Potter’s New Cyclopaedia.) Somehow, beneficial effects were not observed in a double-blind placebo-controlled trial on 40 women with rheumatoid arthritis. (WHO.) graphs.) Taverniera cuneifolia Am. 647 Ayurvedic Dugdh-pheni, Luutaari, Payaswani. |