Unani Arjun
Siddha Marudam.
Action Bark—used as a cardioprotective and cardiotonic in angina and poor coronary circulation; as a diuretic in cirrhosis of liver and for symptomatic relief in hypertension; externally in skin diseases, herpes and leukoderma. Powdered bark is prescribed with milk in fractures
Siddha/Tamil Kattu-ulandu.
Terminalia bellirica Roxb.
and contusions with excessive ecchymosis, also in urinary discharges and strangury. Fruit—deobstruent.
The Ayurvedic Pharmacopoeia of India recommends the powder of the stembark in emaciation, chest diseases, cardiac disorders, lipid imbalances and polyuria.
The bark extract contains acids (arjunolic acid, terminic acid), glycosides (arjunetin, arjunosides I—TV), and strong antioxidants—flavones, tannins, oligomeric proanthocyanidins.
The bark extract (500 mg every 8 h) given to (58 male) patients with stable angina with provocable ischemia on treadmifi exercise, led to improvement in clinical and treadmill exercise parameters as compared to placebo therapy.
These benefits were similar to those
observed with isosorbide mononitrate
(40 mg/day). (Indian Heart 1. 2002,
54(4), 441.)
Arjunolic acid exhibited significant
cardiac protection in isoproterenol induce myocardial necrosis in rats.
(Mol Cell Biochem, 2001, 224 (1 2),
135—42.) A study demonstrated that the
alcoholic extract of Term inalia arjuna
bark augmented endogenous antioxi dan compounds of the rat heart and
prevented from isoproterenol- induced
myocardial ischemic reperfusion in jury (Life Sci. 2003, 73 (21), 2727—
2739.) Cardiac lipid peroxidation in
male Wistar rats was reduced by 38.8%
± 2.6% at a dose of9O mg/kg, in a study
