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Herbs - Medicinal plants usage and Identification Data base
Jupha (Hyssopus officinalis) Medicinal uses, Adverse effects,Research & Pharmacology
Jupha – (Hyssopus officinalis) Medicinal uses, Adverse effects,Research & Pharmacology
Jupha- Hyssopus officinalis is a plant used for the treatment of swelling, constipation, distention of the abdomen, intestinal worms, hepatomegaly, cough and rhinitis.
Latin name- Hyssopus officinalis Linn.
Names in different languages:
Hindi name – Jupha
English name – Hyssop
Malayalam name – Isop
Urdu name – Zufah
Chinese – Ngau sat chou
Dutch – Hysop
French – Hysope, Hese saesu
German – Eisop
Greek – Issopos
Hebrew – Esuv
Hindi – Jupha,
Iceland – Isopus
Italian – Issopo
Japanese – Hissopu
Korean – Harob
Norwegian – Hissopo
Russian – Issop
Spanish – Hisopo
Swedish – Isop
Morphology of Hyssopus officinalis:
Jupha is a small plant spreading in the ground level and is found in the Himalayan belt. The stem is woody at the base, from which grow a number of straight branches. Its leaves are lanceolate, dark green in color, and from 2 to 2.5 cm (0.79 to 0.98 in) long. The leaves have small hair like structure and have a pleasant odor and bitter taste. The flowers are pinkish to purplish in color and have pleasant odor. They bloom from July to September. The fruit is brown in color and slightly triangular in shape.
Rasa (Taste) – Katu (Pungent), Tikta (Bitter)
Guna (Qualities) – Laghu (Light for digestion), Ruksha (Dry in nature), Teekshna (Strong)
Vipaka – Katu (Undergoes Pungent taste after digestion)
Veerya (Potency) – Ushna (Hot)
Karma (Actions) – Kaphavata shamaka (reduces vitiated kapha and vata dosha)
Part used- Whole plant
Dosage- 3 to 6 g powder
Chemical constituents of Hyssopus officinalis:
Hyssop contains terpenoids, including marrubiin; a volatile oil consisting mainly of camphor, pinocamphone and beta-pinene; ﬂavonoids, glucosides, tannins and resin. Marrubiin is a strong expectorant. The plant also contains ursolic acid, an anti-inﬂammatory principle. The alcoholic extract of the aerial parts at ﬂower- ing yields an active antioxidant com- pound, rosmanol-ethyl ether. Its activity is much greater than butylated hydroxyl toluene. Pinocamphone and isopino camphone are toxic constituents of the essential oil.
जूफा तीक्ष्णा कटुतिक्ता वीर्योष्णा कफवातनुत् ।
शोथघ्नी लेखनी पित्तसारणी कृमिनाशिनी॥ ( द्र.गु.)
Uses of Jupha:
- A tea made from the leaves is used in the treatment of flatulence, stomach aches, upper respiratory tract infections, and coughs in children.
- A poultice made from the herb is used to heal wounds.
- The paste of the leaf is applied over wound for healing.
- Cold infusion of the leaf is given in a dose of 40 ml to treat hepatomegaly and fever.
- The paste of the leaf is applied over the forehead to treat rhinitis and headache.
- Fresh juice of the leaf and flower is given in a dose of 10 ml to treat constipation and distention of abdomen.
- The decoction of the leaf is given in a dose of 25 ml to treat intestinal worms.
- The juice of the leaf is given with honey to treat cough and asthma.
- The essential oil is used in aromatherapy. This oil should not be used on people who are highly strung as it can cause epileptic symptoms. This oil should not be used internally expect under professional supervision.
- Externally used as a re-solvent particularly for ecchymosis of eye and eyelids. Oil is used to treat cold cough and lung complains.
Adverse effect of Hyssop: The essential oil of the plant in excess quantity can cause increased intestinal movement and diarrhea. Apart from the above features it can also cause epileptic attack in person susceptible to strong odor.
Ayurvedic medicines containing Jupha:
Gojihwadi kashaya: It is an Ayurvedic medicine in water decoction form. It is used in the treatment of fever, cough, bronchitis, asthma etc.
P-KOF syrup: P-KOF Syrup is a proprietary Ayurvedic medicine indicated in Ayurvedic treatment of cold, cough and allergic conditions.
Research articles related to Hyssopus officinalis:
Anti- asthmatic action: It has been proved that Uygur herb Hyssopus offcinalis L. could affect the levels of some cytokines (such as IL-4, IL-6, IL-17, and IFN-γ) in asthmatic mice. By detection of the expressions of MMP-9 and TIMP-1 and the morphological changes, the aim of this research is to reveal the mechanism of Uygur herb Hyssopus offcinalis L. in the process of airway remodeling. It is suggested that Uygur herb Hyssopus offcinalis L. could inhibit airway remodeling by correcting imbalance of MMP-9/TIMP-1 ratio.
Ulcero protective action: Ethanolic extract of Hyssopus officinalis (EEHO) at the dose of 100 and 125 mg/kg was administered to albino rats 1 hour before the administration of ethanol. Animals were there then sacrificed and tissue homogenate was used for various biochemical parameters in order to explore the ulcero- protective and antioxidant potential of the plant. Administration of 1 ml of ethanol to overnight fasted rats resulted in increased ulcer index, total acidity and decreased pH. The findings of the study indicate that pre-treatment with EEHO has a significant ulcero- protective and antioxidant activity in ethanol-induced ulcers.
Species: H. officinalis
Gana – Traditional classification:
Tulasyadi Varga- Adarsha Nigantu