The bisdesmosidic oleanolic acid saponins have been isolated from the fresh leaves. Significant hepatoprotective activity has been found in the prosaponin from ginsenoside Ro (chiku setsusaponinV); and in coumestans, wedelolactone and demethyl wedelolactone, isolated from the methanol extract of the herb.
Wedelolactone has also been found to be a potent and selective 5-lipoxy- genase-inhibitor, the process being an oxygen radical scavenger mechanism.
Wedelolactone (0.05%), isolated from the leaves, is analogous in structure to coumestrol, an estrogen from
Melilotus sp. (clover).

Withania ashwagandha Kaul (cultivated var.) 717
Wendlandia exserta DC. Wikstroemia indica Mey.
Family Rubiaceae. Synonym W viridifiora Meissn.
W indica var. virdflora Hook. f.
Habitat Sub-Himalayan region,
West Bengal, Madhya Pradesh,
Family Thymelaeaceae.
Andhra Pradesh and Maharashtra. Habitat Eastern Assam; as a weed
Ayurvedic Tilaka. in Tamil Nadu.
Folk Tiiyaa (Bihar), Tilki, Mimri English Small-Leaf Salago.
Folk Salago.
Action Bark—administered in Action Root bark—diuretic,
urinary affections. vesicant, purgative and piscicidal.
The root bark is reported to con tai a flavone glycoside, wikstroemin,
Wendlandia tinctoria DC. which exhibited diuretic activity.
In Chinese folk medicine, the bark
Family Rubiaceae. .
is used for schistosomiasis.
Habitat Sub-Himalayan tract from The stem contains wikstromol, a hg Garhwa eastwards to Bhutan and nm prototype which exhibited anti Khas hills. neoplastic activity. Daphnoretin, iso late from the plant, caused platelet
Ayurvedic Tilak (related species).
aggregation in the blood of rabbits.
Action Bark—used for cramps in A polysaccharide, comprising glucose,
cholera patients. arabinose, galacturonic acid, galactose

Encyclopedia of Ayurvedic Medicinal Plants

A Candle of Medicinal Herb’s Identification and Usage