62 Aristolochia longa Linn.
Aristolochia longa Linn.
English European Birthwort.
Unani Zaraawand Taweel.
Action Oxytocic, abortifacient, emmenagogue.
Aristolochic acid and its Me ester—strongly abortifacient, showed damage to liver and kidney. Roots— anti-oestrogenic. A cytotoxic lignan, savinin, has been isolated from the roots.
Aristolochic acid also has an effect against adenosarcoma and HeLa cells in culture; however, it is suspected to be carcinogenic.
Aristolochia extracts show a pronounced enhancement ofphagocytosis by leucocytes, granulocytes and pentoneal macrophages, due to the presence of aristolochic acids.
Tardolyt-coated tablets, which contain 0.3 mg of aristolochic acid, increase phagocytosis in healthy men.
Aristolochic acid also exhibits reduction of some of the toxic effects of prednisolone, chloramphenicol and tetracycline in experiments in vitro, and a reduction in the rate of recurrent herpes lesions in vivo.
Armoracia lapathifolia Gilib.
Synonym A. rusticana Gaertn et al. Family Crucferae; Brassicaceae.
Habitat Native to Europe; grown
in gardens in northern India and in hill stations of southern India.
Action Circulatory stimulant, diaphoretic, diuretic, antibiotic.
Used for both urinary and respiratory tract infections. Root—liver, spleen and pancreatic stimulant; an alternative to Cayenne pepper; urinary antiseptic; diuretic; used in the treatment of gout, increases excretion of uric acid; also for proteinura and vaginal discharges. An infusion is used for hepatitis.
Key application In catarrhs of the respiratory tract and as a supportive therapy for infections of the urinary tract; externally for catarrhs of the respiratory tract and hyperaemic treatment of minor muscle aches. (German Commission E.) It is contraindicated in stomach and intestinal ulcers and kidney disorders; not to be administered to children under 4 years.
The root contains glucosinolates, mainly sinigrin, which releases allyl isothiocyanate on contact with the enzyme myrosin during crushing. The oil exhibits broad-spectrum antibiotic activity due to allyl