not been reported. (German Commis sio E.)
Berberine is bactericidal, amoebici da and trypanocidal. Berberine is an tidiarrhoeal as it enters into the cytosol
or binds to the cell membrane and in hibit the catalytic unit of andenylate
cyclase. It is active
in vitro and in ani mal against cholera.
Berberine stimulates bile secretion
and shows sedative, hypotensive, anti-
convulsant and uterine stimulant activ it in animals. Alkaloid bermarine is
also strongly antibacterial. It has been
shown to increase white blood cell and
platelet counts in animals with iatro geni leukocytopaenia.
Berberine, berbamine and jatror rhizin are hypotensive and sedative.
Many of the alkaloids are antineo plastic. The alkaloid berbamine (50 mg
three times daily for 1—4 weeks) helped
reverse leukopaenia induced by ben zene cancer chemotherapy or radio therap in a clinical study. (Francis
Brinker.)
Berberine, when combined with
pyrimethamine, was more effective
than combinations with other antibi otic in treating chloroquine-resistant
malaria. (Sharon M. Herr.)
Bergenia ligulata (Wall.) Engl.
Synonym B. ciliata Sternb.
Saxfraga ligulata Wall.

     Family Saxifragaceae.
Habitat Temperate Himalaya from Kashmir to Bhutan, between altitudes of 900 and 3,000 m.
Ayurvedic Paashaanabheda, Ashmaribhedikaa, Ashmaribhit, Ashmghna, Shilaabhit, Shilaabheda. (These synonyms are also equated with
Aerva lanata Juss.)
Siddha/Tamil Padanbethi. Action Leaf and root—antiscorbutic, astringent, spasmolytic, antidiarrhoeal. Used in dysuria, spleen enlargement, pulmonary affections as a cough remedy, menorrhagia, urinary tract infections. Alcoholic extract of roots— antilithic. Acetone extract of rootbark—cardiotoxic, CNS depressant and anti-inflammatory; in mild doses diuretic but antidiuretic in

Encyclopedia of Ayurvedic Medicinal Plants

A Candle of Medicinal Herb’s Identification and Usage